Abstract: A simultaneous determination method for 7 kinds of carbamate residues in vegetables was developed by ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The samples was extracted with acetonitrile and cleaned-up by NH2 solid phase extraction (SPE) cartridges. The analytes were quantified by UPLC-MS/MS in a positive ion multiple reaction mode (MRM). An excellent linear relationship for 7 carbamate residues was observed in the concentration range of 5－200μg/L with the regression coefficients of 0.9977－0.9999. The average recovery rate of 7 carbamate residues in vegetables at the spiked level of 0.01－0.10 mg/kg was in the range of 72.1%－110.2% with relative standard deviation of 1.7%－9.4%. This developed method revealed a detection limit range of 0.5－8.0μg/kg (RSN = 10). Therefore, this developed method is characteristics of simple operation, high sensitivity and precision, which can meet the requirements for simultaneous determination of carbamate pesticide residues in vegetables for inspection and confirmation.

Key words: carbamate, ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), vegetables, pesticide